university of pennsylvania smell identification on iranian population

background university of pennsylvania smell identification test (upsit) is one of the most common smell identification tests to assess olfactory function. objectives the study was conducted to assess the accuracy of university of pennsylvania smell identification test (upsit) in iranian population. materials and methods university of pennsylvania smell identification test was performed on 30 (50%) female and 30 (50%) male, who were healthy adult volunteers. the total mean score as well as mean scores according to the gender were assessed and compared to the upsit classification. odors considered valid and accurate if its correct identification ability rate was more than 70% among study population. results the test score was 25.04 ± 4.92 in female and 23.29 ± 4.23 in male volunteers that all were considered as microsmia according to upsit. sixteen odorants were correctly identified by about 70% of the volunteers and the remains 24 odorants were identified by less than 70%; 7, 5 and 12 odors was identified by60%-70%, 50%-60% and less than 50% of the volunteers, respectively. conclusions according to the results of the study, documented that even less than half of the odors (16 out of 40) were identified correctly by the volunteers, which indicating that the upsit is not a suitable test to evaluate olfactory function in iranian population due to the high amount of unfamiliar smells that should be replaced with more familiar ones.